Use commas to set off nonessential expressions--words, phrases, and clauses that are not necessary for the meaning or structure of the sentence. You can tell whether an expression is nonessential by trying to omit it. If the sentence makes sense and is structurally correct, the expression is nonessential and should be set off by commas.

Nonessential: Let´s talk to Bob, who has experience in this area.
Essential: Let´s talk to someone who has experience in this area.

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